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Abstrait

The impact of drug metabolism on drug design and optimization of prodrugs to metabolite targeting

Rosie Janina

Drug metabolism plays a significant role in drug design and optimization, shaping the pharmacokinetic and pharmacodynamics properties of pharmaceutical compounds. Understanding the metabolic fate of drugs in the body is crucial for enhancing their efficacy, improving safety profiles and maximizing therapeutic outcomes. This article explores the profound impact of drug metabolism on drug design and optimization, highlighting the utilization of prodrugs and metabolite targeting strategies to enhance drug performance